Detalhe da pesquisa
1.
Single-cell transcriptomic profiling of the mouse cochlea: An atlas for targeted therapies.
Proc Natl Acad Sci U S A
; 120(26): e2221744120, 2023 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339214
2.
Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis.
Proc Natl Acad Sci U S A
; 117(49): 31278-31289, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229591
3.
Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.
Proc Natl Acad Sci U S A
; 114(36): 9695-9700, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835534
4.
Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.
J Neurosci
; 31(34): 12241-50, 2011 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21865467
5.
A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.
Proc Natl Acad Sci U S A
; 106(13): 5252-7, 2009 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-19270079
6.
The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses.
iScience
; 25(12): 105628, 2022 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36483015
7.
Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.
J Neurosci
; 30(34): 11259-69, 2010 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20739546
8.
Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.
EMBO Mol Med
; 11(9): e10288, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31448880
9.
Calcium microdomains at presynaptic active zones of vertebrate hair cells unmasked by stochastic deconvolution.
Cell Calcium
; 44(2): 158-68, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18249440
10.
CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival.
EMBO Mol Med
; 9(12): 1711-1731, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084757
11.
Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.
J Cell Biol
; 212(2): 231-44, 2016 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26754646
12.
Presynaptic calcium stores modulate afferent release in vestibular hair cells.
J Neurosci
; 23(17): 6894-903, 2003 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-12890784
13.
EPS8, encoding an actin-binding protein of cochlear hair cell stereocilia, is a new causal gene for autosomal recessive profound deafness.
Orphanet J Rare Dis
; 9: 55, 2014 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24741995
14.
Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice.
J Cell Biol
; 199(2): 381-99, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23045546
15.
Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
J Clin Invest
; 121(12): 4796-809, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22105175
16.
Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human.
Nat Commun
; 2: 201, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21326233
17.
HCN channels are not required for mechanotransduction in sensory hair cells of the mouse inner ear.
PLoS One
; 5(1): e8627, 2010 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20062532
18.
Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.
J Neurophysiol
; 101(6): 2961-73, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19339464
19.
Nature and expression of dihydropyridine-sensitive and -insensitive calcium currents in hair cells of frog semicircular canals.
Pflugers Arch
; 446(2): 189-97, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12684799